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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.
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Search Within Results
Keyword Search:
136 – 150 of 1,264 results
136

Medchemexpress LLC m-PEG11-NHS ester | 3119903-67-9 | C28H51NO15 | 100 MG
SDP

m-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is recommended for storage at -20°C, sealed, and away from moisture and light. If in solvent, it can be stored at -80°C for 6 months or -20°C for 1 month, also with sealed storage, away from moisture and light.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Store at -20°C, sealed, away from moisture and light
  • Extended storage in solvent possible at -80°C

ENCOMPASS_PREFERRED
137

eMolecules​ 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208

Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208

ENCOMPASS_PREFERRED
138

Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
SDP

Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).

  • Biotin-conjugated probe for affinity capture and pull-down assays.
  • Derived from a BTK inhibitor for target-specific engagement.
  • Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
  • High purity suitable for research applications (>99.6%).
  • Available as solid material and as a 10 mM solution in DMSO.
  • Molecular weight approximately 1,097.37 g/mol.

ENCOMPASS_PREFERRED
139

eMolecules​ 58-85-5 | D-(+)-Biotin | Apollo Scientific | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212

D-(+)-Biotin | Apollo Scientific | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212

ENCOMPASS_PREFERRED
140

eMolecules​ 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733

Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733

ENCOMPASS_PREFERRED
141

Medchemexpress LLC exo-BCN-NHS carbonat 25mg
SDP

exo-BCN-NHS carbonate carbonate contains BCN group Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups

ENCOMPASS_PREFERRED
142

Medchemexpress LLC Azido-PEG9-NHS ester | 2801772-87-0 | 98.0% | C25H44N4O13 | 100 MG
SDP

Azido-PEG9-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It serves as a click chemistry reagent, featuring an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules. This ester can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.

  • Peg-based protac linker
  • Used in the synthesis of protacs
  • Functions as a click chemistry reagent
  • Contains an azide group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction
  • Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions

ENCOMPASS_PREFERRED
143

Medchemexpress LLC Biotin-TAT (47-57) | 1231898-25-1 | 98.6% | 1786.12 | 10 MG
SDP

Biotin-TAT (47-57) is a biotin-tagged transactivator of transcription, identified as one of the most widely used protein transduction domains (PTDs). Its entry into various primary cells is ATP- and temperature-dependent, suggesting the involvement of endocytosis.

  • Biotin-tagged
  • Functions as a transactivator of transcription
  • Acts as a widely used protein transduction domain (PTD)
  • Entry into primary cells via an ATP- and temperature-dependent mechanism
  • Involvement of endocytosis in cellular uptake
  • Useful in peptide and derivatives research
  • Applicable in peptide for drug delivery
  • Functions as a cell-penetrating peptide
  • Identified as a fluorescent dye

ENCOMPASS_PREFERRED
144

Medchemexpress LLC DBCO-PEG3-NHS | 2249926-63-2 | 98.0% | 591.61 | 50 MG
SDP

DBCO-PEG3-NHS is a biochemical assay reagent designed for the chemical modification of proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. It serves as a linker in PROTAC synthesis, drug delivery, and the development of biosensors and diagnostic reagents.

  • Used for chemical modification of proteins and antibodies with alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester groups.
  • Can be utilized as a linker in PROTAC synthesis.
  • Applicable for drug delivery.
  • Useful in the development of biosensors.
  • Aids in the development of diagnostic reagents.

ENCOMPASS_PREFERRED
145

Medchemexpress LLC Boc-N-PEG1-C2-NHS ester | 1260092-55-4 | 97.0% | C14H22N2O7 | 1 G
SDP

Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • PEG-based PROTAC linker
  • Can be used in the synthesis of PROTACs
  • Exploits the intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins

ENCOMPASS_PREFERRED
146

Medchemexpress LLC 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(1,1-dimethylethyl) 20-(2,5-dioxo-1-pyrrolidinyl) ester | 2055040-78-1 | 96.9% | 506.54 | 1 G
SDP

Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound facilitates the targeted degradation of proteins by exploiting the intracellular ubiquitin-proteasome system.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Exploits the intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins

ENCOMPASS_PREFERRED
147

Medchemexpress LLC Azido-PEG3-O-NHS ester | 2110448-98-9 | 95% | C13H20N4O8 | 100 MG
SDP

Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group-containing molecules.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Click chemistry reagent
  • Contains an azide group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
  • Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups

ENCOMPASS_PREFERRED
148

Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 g/mol | C10H16N2O3S | 50 MG
SDP

L-biotin is the unnatural enantiomer of biotin supplied as a high-purity research reagent for laboratory use (not for human or clinical applications).

  • High purity (reported 99.5-99.7%).
  • Cas number 21788-37-4.
  • Molecular weight 244.31 g/mol.
  • Chemical formula C10H16N2O3S.
  • Available in small milligram quantities such as 50 MG.

ENCOMPASS_PREFERRED
149

Medchemexpress LLC Bis-PEG9-NHS ester 1g | 1008402-79-6 | 1 G
SDP

Bis-PEG9-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester groups. It reacts with primary amines to form stable amide bonds and is used for protein conjugation, PROTAC and antibody-drug conjugate (ADC) linker synthesis. Provided as a high-purity research reagent.

  • Homobifunctional PEG9 spacer with two NHS ester reactive groups.
  • Enables amine-targeted conjugation to proteins and small molecules.
  • PEG spacer increases aqueous solubility and reduces aggregation.
  • Suitable for PROTAC and ADC linker synthesis and general bioconjugation.
  • High purity for consistent research results.

ENCOMPASS_PREFERRED
150

eMolecules​ 943858-70-6 | N3-C3-NHS ester | TargetMol | MFCD22573606 | 226.192 | C8H10N4O4 | 0.000 | [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O | 25mg | 799230477

N3-C3-NHS ester | TargetMol | 943858-70-6 | MFCD22573606 | 226.192 | C8H10N4O4 | 0.000 | [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O | 25mg | 799230477

ENCOMPASS_PREFERRED