Biotin and derivatives
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa
Medchemexpress LLC Undecanoic acid, biotinyl N-hydroxysuccinimide ester | 887628-40-2 | MFCD05865045 | 99.5% | C25H40N4O6S | 10MG
Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that provides an NHS-activated biotinylation reagent for conjugation to primary amines. It is intended for research use in chemical synthesis and bioconjugation workflows, enabling introduction of a biotin affinity tag for purification and detection; follow the manufacturer datasheet and COA for handling and storage instructions.
- NHS-activated ester for efficient amine coupling.
- 10-carbon spacer to reduce steric hindrance during binding.
- Introduces a biotin tag for affinity purification and detection.
- High purity suitable for synthetic and analytical applications.
- Supplied with datasheet and certificate of analysis for quality verification.
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | MFCD22683276 | 98.0% | 476.48 g/mol | C19H32N4O10 | 25 MG
Azido-PEG6-NHS ester is a bifunctional PEG-based reagent containing an azide group for bioorthogonal click chemistry and an N-hydroxysuccinimide (NHS) ester for coupling to primary amines. It is commonly used as a linker in antibody-drug conjugate and PROTAC synthesis, and for general bioconjugation applications.
- Bifunctional: azide for CuAAC/SPAAC and NHS ester for amine coupling.
- PEG6 spacer improves solubility and reduces steric hindrance.
- High purity for reliable conjugation reactions.
- Suitable for ADC and PROTAC linker installation and bioconjugation workflows.
- Available in small-scale packaging compatible with research applications.
Medchemexpress LLC Biotin-PEG3-NHS ester | 1253286-56-4 | 98.4% | 25 MG
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTAC.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
eMolecules Ambeed m-PEG8-NHS ester 100mg 714088003 A703316 0 000 756525-90-3 MFCD13184969 509 549 C22H39NO12
Ambeed m-PEG8-NHS ester 100mg 714088003 A703316 0 000 756525-90-3 MFCD13184969 509 549 C22H39NO12
Sigma Aldrich Fine Chemicals Biosciences Albumin biotin labeled bov10MG
ALBUMIN Albumin biotin labeled bov10MG
Apexbio Technology LLC Cy3 NHS ester(Et)(Synonyms: Cy3 NHS ester, Cy3 NHS Ester (ethyl), Cyanine3 NHS ester, Cyanine 3 NHS ester, Cy3 Mono NHS Ester), 25mg.
Cy3 NHS ester(Et) is a small molecule commonly employed in biomedical research as a reactive fluorescent reagent Through its N-hydroxysuccinimide (NHS) ester functionality it readily forms stable covalent linkages with primary amine groups present on proteins peptides and other biomolecules Due to its fluorescent character Cy3 NHS ester(Et) is extensively utilized for labeling biological targets enabling visualization and tracking in fluorescence microscopy and imaging analyses This property facilitates investigations into molecular localization trafficking processes and pathology-associated pathways in various experimental models
Medchemexpress LLC Bis-SS-C3-NHS ester | 98604-88-7 | 98.0% | 432.47 | C16H20N2O8S2 | 1 G
Bis-SS-C3-NHS ester is a disulfide-cleavable N-hydroxysuccinimide (NHS) ester linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It couples to primary amines via NHS-ester chemistry and releases payloads under reducing intracellular conditions.
- Molecular weight: 432.47
- Chemical formula: C16H20N2O8S2
- Cas number: 98604-88-7
- Purity: 98.0%
- Appearance: white to off-white solid
- Reactive group: NHS ester for coupling to primary amines
- Application: cleavable disulfide linker for ADC synthesis and bioconjugation
- Available pack size: 1 g
Medchemexpress LLC Azido-PEG8-NHS ester | 1204834-00-3 | 98.0% | 564.6 g/mol | C23H40N4O12 | 25 MG
Azido-PEG8-NHS ester is an 8-unit polyethylene glycol (PEG) bifunctional linker bearing an azide on one terminus and an N-hydroxysuccinimide (NHS) ester on the other. It is used for bioconjugation: the azide enables azide-alkyne cycloaddition (copper-catalyzed or strain-promoted), while the NHS ester reacts with primary amines to form stable amide bonds.
- Azide enables copper-catalyzed and strain-promoted click chemistry.
- N-hydroxysuccinimide ester labels primary amines (for lysine and amine-modified substrates).
- PEG8 spacer increases hydrophilicity and improves solubility in organic and mixed solvents.
- Soluble in DMSO, dichloromethane, and DMF.
- Commonly used as an ADC or PROTAC linker and general bioconjugation reagent.
- Store at -20 °C to preserve stability.
Chem-Impex International, Inc. Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester | 72040-63-2 | MFCD00065502 | 100MG
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester, 72040-63-2, MFCD00065502, 100MG
Chem-Impex International, Inc. Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester | 72040-63-2 | MFCD00065502 | 250MG
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester, 72040-63-2, MFCD00065502, 250MG
Medchemexpress LLC Biotin-sar-oh | 154024-76-7 | 315.39 | C13H21N3O4S | 1 G
Biotin-sar-oh is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin functionality, used in the synthesis of antibody-drug conjugates and probe development.
- Cleavable ADC linker for conjugation and release strategies.
- Biotinylated for affinity capture and detection.
- Molecular formula: C13H21N3O4S; molecular weight: 315.39.
- Available pack sizes: 250 mg and 1 g.
- CAS number: 154024-76-7.
Medchemexpress LLC N-succinimidyl-3-(2-pyridyldithio)butyrate | 107348-47-0 | MFCD28398150 | 98.3% | 326.4 g/mol | C13H14N2O4S2 | 1 G
PPC-NHS ester (N-succinimidyl-3-(2-pyridyldithio)butyrate, CAS 107348-47-0) is an NHS-activated cleavable linker reagent used for conjugating small molecules to proteins and antibodies. It reacts with primary amines to form stable amide bonds and contains a pyridyldisulfide moiety that enables controlled cleavage under reducing conditions, making it suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Reacts with primary amines to form stable amide bonds.
- Contains a pyridyldisulfide cleavable linkage for controlled release under reducing conditions.
- High purity suitable for conjugation workflows (≈98.3%).
- Compatible with common aqueous and organic conjugation conditions.
Medchemexpress LLC NHS-modified MMAF (trifluoroacetate) | 96.0% | 1165.34 | C57H87F3N8O14 | 50 MG
NHS-modified MMAF (trifluoroacetate) is an NHS-activated derivative of monomethyl auristatin F provided as the trifluoroacetate salt. It is used as a synthetic intermediate for preparing antibody-drug conjugate payload-linker constructs via NHS-ester-mediated conjugation to amines on antibody binders.
- NHS-activated derivative for conjugation chemistry.
- Provided as the trifluoroacetate salt for stability.
- High purity suitable for research and ADC synthesis.
- Available in research-scale quantities for lab use.
- Documented with COA and SDS for quality and safety information.